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- W2371117998 abstract "The impact of MCE on antibacterial effect of pathogenic microorganism,growth performance of weaner piglets,serum immune stress and antioxidant parameters were studied E.coli,Salmonella,Staphylococcus aureus and Bacillus subtilis were chosen.The antibacterial effect of MCE differential levels and minimum inhibited consistency were determined.The skin fibroblasts cells of pigs were selected and cultured.The cells were stimulated with 10μg/mL Lipopolysaccharides(LPS)and the cell stress model was conducted.MCE were added respectively until the finished concentration reached to 0(the control group),50ng/mL,100ng/mL,150ng/mL.The final concentration of oxytetracycline reaching 50μg/mL was as the positive control.After cultured 24h,Immunoglobulin(IgG)and Lysozyme(LSZ)were determined.In the animal experiment,60PIC quinary crossbred piglets were chosen and were weaned at 35days of age,and their trial period was 25days.Randomly,they were divided into five process groups,four repeat for each group,and 3piglets for every repeat.In each treatment,basal diets supplemented with 0(control group),2.5mg/kg,5.0mg/kg,7.5mg/kg MCE were fed,and terramycin group was fed the basal diet adding 50mg/kg of terramycin.When the piglets were at 60days of age,the serum immune stress and antioxidant parameters were confirmed.The results showed that MCE had inhibitory effect on Gramnegative bacteria(E.coli,Salmonella),Gram-positive bacteria(Staphylococcus aureus)and Bacillus subtilis.Except for moderately sensitive to Salmonella,it was highly sensitive to other three kinds of microbes.Minimum inhibited consistency of MCE for E.coli,Salmonella,Staphylococcus aureus,Bacillus subtilis respectively were 1 280μg/mL,1 280μg/mL,2 560μg/mL,2 560μg/mL.Adding 5.0mg/kg MCE significantly improved piglets' average daily gain and feed intake(P0.05),and decreased the material weight rate(P0.05).MCE significantly improved the content of IgG and LSZ in serum of weaned piglets(P0.01),and significantly reduced MDA content in serum(P0.01).Compared with the antibiotics group,MCE significantly increased SOD in serum(P0.01),reduced serum MDA content(P0.01).After the cells were stimulated by LPS,adding different concentrations of MCE significantly improved IgG and LYS content of cell(P0.01),and it was significantly higher than that of the oxytetracycline groups(P0.01).The results suggested that MCE substituted antibiotics was feasible in piglet growth." @default.
- W2371117998 created "2016-06-24" @default.
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- W2371117998 date "2013-01-01" @default.
- W2371117998 modified "2023-09-28" @default.
- W2371117998 title "Effect of Macleaya Cordata Extract on Piglet Production" @default.
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