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- W2371141691 abstract "Objective To investigate the TLR4 expression in the coronary atherosclerotic plaque with acute coronary artery lesions and its relationship with the acute coronary artery lesions. Methods Twenty-four cases and heart samples autopsied in our department from 2004 to 2007 were selected and divided into 3 groups of the experimental group, control group A and control group B (8 cases in each group). The TLR4 expressive change in the coronary atherosclerotic plaque of each group and their average optical densities (OD values) were detected by the immunohistochemistry (SABC method) and image analysis technology. All data and the difference among groups were analyzed statistically. Results The strong positive expression of TLR4 was found in the experimental group, positive expression in the control group A, and negative expression in the control group B. The result of statistical analysis indicated that the difference of OD value of the TLR4 expression in the coronary atherosclerotic plaques was of statistical significance between the experimental group (0.4662±0.0190) and the two control groups (0.3361±0.0165, 0.2463±0.0190) respectively, and between the control group A and B. Conclusion The expressive change of TLR4 in the coronary atherosclerotic plaque can be regard as an important marker of pathological diagnosis of acute coronary artery lesions, and as an important evidence to diagnose sudden coronary death." @default.
- W2371141691 created "2016-06-24" @default.
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- W2371141691 date "2009-01-01" @default.
- W2371141691 modified "2023-09-27" @default.
- W2371141691 title "A study of TLR4 expression in the coronary atherosclerotic plaque with acute coronary artery lesions" @default.
- W2371141691 hasPublicationYear "2009" @default.
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