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- W2371148049 abstract "AmphiDC-like has a close relationship to human dendritic cell proteins.The full length of AmphiDC-like of Qingdao amphioxus neurula was cloned from a cDNA library by primer walking approach,then sequenced.The deduced amino acid sequence were analyzed and compared with its homologs in Caenorhabditis elegans,Drosophila melanogaster,Danio rerio,Xenopus laevis,Mus musculus,Gallus gallus,Pan troglodytes and Homo sapiens.The results have shown that the obtained AmphiDC-like contained an open reading frame encoding a putative protein of 375 amino acid residues with a PCI domain that was highly conserved in the dendritic cell proteins among other species.The phylogenetic analysis exhibited a high-degree conservation of the AmphiDC-like in vertebrates.The gene AmphiDC-like was found to be expressed in the intestine and the gills by in situ hybrization and could be up-regulated 6 to 48 hours after the Vibrio Parahemolyticus(Vp)challenge as determined by real-time PCR analysis.Our findings will facilitate the subsequent investigations of the amphioxus AmphiDC-like fuctions." @default.
- W2371148049 created "2016-06-24" @default.
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- W2371148049 date "2008-01-01" @default.
- W2371148049 modified "2023-09-25" @default.
- W2371148049 title "Cloning and Expression Pattern Analysis of AmphiDC-like in Amphioxus" @default.
- W2371148049 hasPublicationYear "2008" @default.
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