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- W2371197569 abstract "Objective To evaluate the clinical effect and safety of naloxone plus noninvasive mechanical ventilation in the treatment of patients with chronic obstructive pulmonary disease( COPD) complicated with pulmonary encephalopathy.Methods 84 COPD patients complicated with pulmonary encephalopathy were randomly divided into the experiment group and the control group.The control group was treated with clinical routine therapy and noninvasive ventilation,and the experiment group was additionally treated with naloxone on the basic of the control group.The clinical effect was observed and compared between the two groups.Results The effective rate was 88.10% in the experiment group and 64.29% in the control group respectively,with significant difference.The rate of endotracheal intubation and the average consciousness recovery time were obviously lower in the experiment group than in the control group.The improvement of blood gas analysis indexes 24 hours after the treatment was more pronounced in the experiment group than in the control group( P 0.05).Conclusion Naloxone combined with noninvasive mechanical ventilation has good clinical curative effect and high safety in the treatment of COPD patients complicated with pulmonary encephalopathy." @default.
- W2371197569 created "2016-06-24" @default.
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- W2371197569 date "2013-01-01" @default.
- W2371197569 modified "2023-09-25" @default.
- W2371197569 title "Analysis of clinical effect and safety of naloxone combined with noninvasive mechanical ventilation in the treatment of patients with pulmonary encephalopathy complicated with chronic obstructive pulmonary disease" @default.
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