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- W2371221349 abstract "Objective To investigate the inhibition effect against transplatation tumors H22 , EAC and S180 by abdominal cavity injection of THY-110 in mice.Method Mice were divided into five groups including three drug groups i.e. with THY-110 dose of 80, 120 and 180 mg/kg and a negative(glucose injection) group and a positive drug(fluorouracil) group. 0.2 ml(1×107/ml)tumor cell solution were inoculated to mice at forelimb oxter. After inoculation,mice were continuous injected of THY-110 in 9 days,and then tumors tissue were peeled off and weighed. The inhibitory rate of tumors were calculated based on tumors weight.Result The average tumor inhibitory rates of THY-110(180 mg/kg) against H22,EAC,S180 were 61.2±2.55%,65.7±1.25%,74.0±1.25% respectively,and that of positive drug group was 61.8±7.7%. Conclusion THY-110 has a distinct effect for inhibiting H22 , EAC and S180 transplation tumors in mice." @default.
- W2371221349 created "2016-06-24" @default.
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- W2371221349 date "2007-01-01" @default.
- W2371221349 modified "2023-09-24" @default.
- W2371221349 title "Inhibition Effect of Nolatrexed Dihydrochloride on Transplatation Tumors" @default.
- W2371221349 hasPublicationYear "2007" @default.
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