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- W2371303310 abstract "PURPOSE: To assess the predictive values of clinical examination, X-ray, CT, MRI and intraoperative examination in detecting mandible involvement of oral squamous cell carcinoma(SCC). METHODS: 49 patients with oral SCC treated with primary resection in Cancer Hospital of Peking Union Medical College and Chinese Academy of Medical Sciences between 1993 and 2004 were reviewed retrospectively. All patients were pathologically confirmed to be squamous cell carcinoma. The results of clinical examination, X-ray, CT, MRI and intraoperative examination were compared with the pathological results with SPSS13.0 software package to analyze the predictive capabilities of these methods in detecting mandible involvement and the value in guiding operations. RESULTS: The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of mandible invasion were 42.9% (9/21),100%(28 / 28),100% (9/9),70.0%(28/40) and 75.5%(37/49) by clinical examination; 90.5% (19/21),75.0%(21/28),73.1%(19/26),91.3% (21/23), 81.6%(41/49) by intraoperative examination; The sensitivity of X-ray, CT, MRI were 100%(2/2), 83.3%(10/12), 40%(2/5), respectively;the specificity were 100%(5/5), 100%(11/11), 100%(2/2), respectively. Twenty-eight uninvolved mandibles were resected, including 20 marginal and 8 segmental mandibulectomy. For 21 mandibles with invasion, 3 marginal and 18 segmental mandibulectomy were performed. No significant difference in survival rate was found between different operative methods. CONCLUSIONS: Pre-operative assessment with combined clinical examinations and radiographic evaluations are adequate for mandible invasion in oral SCC and valid for mandibular conservation surgery." @default.
- W2371303310 created "2016-06-24" @default.
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- W2371303310 date "2006-01-01" @default.
- W2371303310 modified "2023-09-26" @default.
- W2371303310 title "The diagnostic accuracy of different methods in assessment of mandible involvement in oral squamous cell carcinoma and subsequent management" @default.
- W2371303310 hasPublicationYear "2006" @default.
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