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- W2371307894 abstract "Porous poly(N-isopropylamide-co-acrylamide)[P(NIPAm-co-AAm)]hydrogels were prepared by freezing polymerization method.With bovine serum albumin(BSA)as the model drug,it was loaded into porous P(NIPAm-co-AAm)hydrogel by post-fabrication encapsulation technique.The loading efficiency and release ratio of model drug were investigated.The influence of different dry processing method on the controlled drug release properties of the drug-loaded hydrogel was also studied.The results showed that creating an interconnecting pore structure within the hydrogel matrices was an effective strategy to improve the drug loading efficiency and the cumulative released amount.In vitro BSA release from the hydrogels exhibited that dry processing method played a dominant role in the controlled drug release properties of P(NIPAm-co-AAm)hydrogel.The drug-loaded hydrogel with the refrigerator freeze-drying treatment showed better sustained drug release of protein drugs." @default.
- W2371307894 created "2016-06-24" @default.
- W2371307894 creator A5030970036 @default.
- W2371307894 date "2013-01-01" @default.
- W2371307894 modified "2023-09-25" @default.
- W2371307894 title "Study on drug releasing properties of porous P(NIPAm-co-AAm) hydrogels" @default.
- W2371307894 hasPublicationYear "2013" @default.
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