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- W2371313841 abstract "Objective: To screen the antidepressant effects of different fractions from Xiao Chaihu decoction.Method: Male Kunming mice were randomly divided into 10 groups: control group,fluoxetine and the petroleum ether extract(part Ⅰ),ethyl acetate extract(part Ⅱ),butanol extract water saturated butanol extract(part Ⅲ) and residual water layer extract(part Ⅳ) of the Xiao Chaihu decoction.The treatment groups received part Ⅰ-Ⅳ at dose of 9.0,18.0 g.kg-1 and fluoxeine at 20 mg.kg-1 for 7 days respectively.The tail suspension test(TST) and forced swimming test(FST) were carried out to compare the antidepressant effects of different fractions from Xiao Chaihu decoction at 1 hour after the last administration.Result: The group of part Ⅱ and part Ⅲ could significantly shorten mice immobility time in FST and TST(P 0.05 or P 0.01).Conclusion: The antidepressant pharmacodynamic tests shows that ethyl acetate extract and butanol extract can be initially determined as the antidepressant effective fraction of Xiao Chaihu decoction." @default.
- W2371313841 created "2016-06-24" @default.
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- W2371313841 date "2013-01-01" @default.
- W2371313841 modified "2023-09-24" @default.
- W2371313841 title "Screening of Antidepressant Effects of Different Fractions from Xiaochaihu Decoction" @default.
- W2371313841 hasPublicationYear "2013" @default.
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