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- W2371322729 abstract "Objective To discuss the cell metabolic features and the changes of metabolite in each period of cerebral infarct,and to look for the reliability index which can reflect the cerebral ischemia injury,so to provide pathophysiological basis for the clinical treatment of cerebral infarction in different periods.Materials and Methods According to the time after the attack,100 cases selected with cerebral infarct were divided into groups:(1)superacute group,6h,n=10;(2) acute group,6h-48h,n=52;(3)subacute group,2d-6w,n =25;and(4)chronic group,6w,n=13.PRESS/(TR1500ms,TE135ms) and single voxel acquisition of bilateral corresponding VOL was made.Looking for the changes of NAA and Lac in each period of cerebral infarct,and the normal side was taken as control group.Results During the superacute stage (n=10),Lac appeared,but NAA showed no marked alteration;In acute stage (n=52),Lac was increased,NAA began to decrease in different degrees,In subacute stage(n=25),Lac began to decrease in 17 cases but maintaining a higher level of concentration,and Lac couldn't be found in the other 8 cases,NAA continued to low down;In the chronic stage(n=13),Lac showed could still be detected in 11 cases and couldn't be found in 2 cases.Conclusion The changes of NAA and Lac are reliable indexes reflecting ischemic injury.1HMRS can noninvesively monitor material and energetic metabolism in cerebral infarction,providing objective basis for clinical treatment and prognosis estimation in cerebral infarction." @default.
- W2371322729 created "2016-06-24" @default.
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- W2371322729 date "2011-01-01" @default.
- W2371322729 modified "2023-09-27" @default.
- W2371322729 title "The Clinical Significance of 1HMRS with NAA and Lac in Each Period of Cerebral Infarct" @default.
- W2371322729 hasPublicationYear "2011" @default.
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