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- W2371444340 abstract "[Objective] To compare the effects of Penehyclidine Hydrochloride and Atropine in terms of premedication in total intravenous general anesthesia of elder patients. [Methods] Sixty who received elder patients abdominal sugery were randomly allocated into two group equally: group A were given penehyclidine hydrochloride 0.012 mg/kg iv; group B were given atropine 0.008 mg/kg iv, blood pressure, heart rate, SpO2, oral dryness condition and the level of sedation were monitored in 10, 20, 30 min after administration. [Result] There were no significant differences of age, sex, body weight and height beteew the two groups(P 0.05). In group A, there was no obvious change in heart rate(P 0.05); in group B heart rate increased severely compared with the basic value, the same was true for oral dryness(P 0.05), but there was no difference between the two groups in oral dryness(P 0.05). Group A′s sedation was better than group B(P 0.05). [Conclusion] Penehyclidine Hydrochloride has effects of inhibiting secretion of salivary glands, maintaining cardiovascular stability and central nervous system sedation, helps to prevent awareness during operation, so it is ideal premedication for elder patient." @default.
- W2371444340 created "2016-06-24" @default.
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- W2371444340 date "2008-01-01" @default.
- W2371444340 modified "2023-09-23" @default.
- W2371444340 title "Comparison of Penehyclidine Hydrochloride and Atropine used as premedication of total intravenous general anesthesia in elder patients" @default.
- W2371444340 hasPublicationYear "2008" @default.
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