Matches in SemOpenAlex for { <https://semopenalex.org/work/W2371447417> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2371447417 abstract "Objective To prove the thesis of nonenzymatic glycation inducing aging. Methods Using Dgalactose aging model, we measured the aging effects of Dgalactose, Lglucose, advanced glycosylaton endproducts (AGE), and the inhibiting effect of aminoguanidineHCL (AG) on Dgalactose through determination of spontaneous motor activity, stepthrough test, proliferation rate of lymphocytes, IL2 activity, and SOD activity. Furthermore, we detected the AGE content in serum through specific ELISA. Results We found that Dgalactose, Lglucose, and AGE all could cause the same effect as aging. AG could inhibit the effect of Dgalactose. Higher contents of AGE were detected in serum of old mice and young mice given Dgalactose or Lglucose. AG could lower the AGE content produced in the presence of Dgalactose. Conclusions The aging effect of Dgalactose results from nonenzymatic glycation induced by galactose and the amplification of the production of free radicals and then of itself. Nonenzymatic glycation may play an important role in aging." @default.
- W2371447417 created "2016-06-24" @default.
- W2371447417 creator A5008171665 @default.
- W2371447417 date "1999-01-01" @default.
- W2371447417 modified "2023-09-25" @default.
- W2371447417 title "The demonstration of the thesis of nonenzymatic glycation inducing aging" @default.
- W2371447417 hasPublicationYear "1999" @default.
- W2371447417 type Work @default.
- W2371447417 sameAs 2371447417 @default.
- W2371447417 citedByCount "0" @default.
- W2371447417 crossrefType "journal-article" @default.
- W2371447417 hasAuthorship W2371447417A5008171665 @default.
- W2371447417 hasConcept C126322002 @default.
- W2371447417 hasConcept C134018914 @default.
- W2371447417 hasConcept C139066938 @default.
- W2371447417 hasConcept C147990577 @default.
- W2371447417 hasConcept C170493617 @default.
- W2371447417 hasConcept C185592680 @default.
- W2371447417 hasConcept C2778173381 @default.
- W2371447417 hasConcept C500499127 @default.
- W2371447417 hasConcept C55493867 @default.
- W2371447417 hasConcept C71924100 @default.
- W2371447417 hasConceptScore W2371447417C126322002 @default.
- W2371447417 hasConceptScore W2371447417C134018914 @default.
- W2371447417 hasConceptScore W2371447417C139066938 @default.
- W2371447417 hasConceptScore W2371447417C147990577 @default.
- W2371447417 hasConceptScore W2371447417C170493617 @default.
- W2371447417 hasConceptScore W2371447417C185592680 @default.
- W2371447417 hasConceptScore W2371447417C2778173381 @default.
- W2371447417 hasConceptScore W2371447417C500499127 @default.
- W2371447417 hasConceptScore W2371447417C55493867 @default.
- W2371447417 hasConceptScore W2371447417C71924100 @default.
- W2371447417 hasLocation W23714474171 @default.
- W2371447417 hasOpenAccess W2371447417 @default.
- W2371447417 hasPrimaryLocation W23714474171 @default.
- W2371447417 hasRelatedWork W1518069543 @default.
- W2371447417 hasRelatedWork W1964537401 @default.
- W2371447417 hasRelatedWork W1978995538 @default.
- W2371447417 hasRelatedWork W2017726031 @default.
- W2371447417 hasRelatedWork W2041875988 @default.
- W2371447417 hasRelatedWork W2092578957 @default.
- W2371447417 hasRelatedWork W2095398632 @default.
- W2371447417 hasRelatedWork W2096994711 @default.
- W2371447417 hasRelatedWork W2103058681 @default.
- W2371447417 hasRelatedWork W2126346844 @default.
- W2371447417 hasRelatedWork W2138774341 @default.
- W2371447417 hasRelatedWork W2153282847 @default.
- W2371447417 hasRelatedWork W2186375755 @default.
- W2371447417 hasRelatedWork W2330618556 @default.
- W2371447417 hasRelatedWork W2390543254 @default.
- W2371447417 hasRelatedWork W2471300363 @default.
- W2371447417 hasRelatedWork W2760350769 @default.
- W2371447417 hasRelatedWork W2796260240 @default.
- W2371447417 hasRelatedWork W2944467599 @default.
- W2371447417 hasRelatedWork W2900585145 @default.
- W2371447417 isParatext "false" @default.
- W2371447417 isRetracted "false" @default.
- W2371447417 magId "2371447417" @default.
- W2371447417 workType "article" @default.