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- W2371473721 abstract "Objective To investigate the dynamic change of brain natriuretic peptide(BNP)in chronic heart failure(CHF)and the relationship between BNP and the improvement of heart failure.Methods We studied 54 patients with CHF [32 males and 22 females,average age(58.63±10.32)years] and 52 healthy individuals [30 males and 22 females,average age(57.36±11.41)years] were recruited to control group.Plasma level of BNP was measured by IMRA method and all patients with CHF underwent 6MWT based on Bittner before and 1 month and 3 months after standard anti-CHF therapy.Other parameters of cardiac function were measured by ultrasound.Results The plasma BNP level in the patients with CHF was markedly increased but it was significantly reduced 1 month after treatment while the parameters of the cardiac function have no change.The plasma level of BNP was further reduced with a notable increase of 6MWT,CO,CI,and EF 3 months after treatment.And the patients'symptoms and tolerance of exercise were greatly improved.Conclusion The decrease of BNP in CHF was prior to the changes of the parameters of the cardiac function and this change of cardiac endocrine could be beneficial to the improvement of heart failure." @default.
- W2371473721 created "2016-06-24" @default.
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- W2371473721 date "2006-01-01" @default.
- W2371473721 modified "2023-09-25" @default.
- W2371473721 title "Dynamic change of brain natriuretic peptide during the improvement of heart failure" @default.
- W2371473721 hasPublicationYear "2006" @default.
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