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- W2371486215 abstract "Objective To survey the effect of mifepristone integrated with misoprostol on the transcription levels of PR-mRNA,ER-mRNA and the expression levels of PR,ER in the villus and decidua from women in early pregnancy. Methods The trial group of the present study was composed of 2 women in early pregnancy who were subjected to the drug-indueed abortion,the drug being mifepristone integrated with misoprostol.1 women subjected to artificial abortion served as controls FQ(fluorescent quantitative)-PCR was adopted to detect the transcription levels of PR-mRNA and ER-mRNA in the villus and decidua from the women of both groups while the levels of expression of PR and ER in the villus and decidua from these women were assayed with immunochemical methods. Results The transcription levels of ER-mRNA and PR-mRNA as well as the expression levels of ER and PR were significantly lower in the villi and deciduas from women subjected to the drug-induced abortion as compared with those from women of the control group(P0.01,P0.01). Conclusion The effect of mifepristone integrated with misoprostol to terminate early pregnancy may be related to its influence on the transcription levels of ER-mRNA and PR-mRNA as well as expression levels of ER and PR in the villus and decidua." @default.
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- W2371486215 date "2007-01-01" @default.
- W2371486215 modified "2023-09-22" @default.
- W2371486215 title "Effect of Mifepristone Integrated with Misoprostol on the Transcription Levels of PR-mRNA,ER-mRNA and the Expression Levels of PR,ER in the Villus and Decidua from Women in Early Pregnancy" @default.
- W2371486215 hasPublicationYear "2007" @default.
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