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- W2371489664 abstract "Objective To study the effects of alcoholic extracts of Averrhoa carambola L.root on blood glucose level and lipid peroxidation in STZ-induced diabetic mice.Methods Diabetic model were induced by once intraperitoneal injection of STZ.Diabetic mice were randomly divided into model group,glibenclamide group and high-and low-doses of alcoholic extracts of Averrhoa carambola L.root groups.At the same time,there were ten mice in normal group.The experimental mice were intragastric administration respectively for 14 days.The level of fasting blood glucose(FBG) were observed after treatment with drugs on 0d,7th,14th day.The experimental mice were killed on the 14th day.Activity of SOD and concentration of MDA in liver were determined.Results The fasting blood glucose of high-and low-doses of alcoholic extracts of Averrhoa carambola L.root groups were decreased significantly(P0.01).Activity of liver SOD in high-dose of alcoholic extracts of Averrhoa carambola L.root group significantly increased(P0.05),while concentration of MDA in liver decreased markedly(P0.01).Conclusion The alcoholic extracts of Averrhoa carambola L.root could relieve the reaction of lipid peroxide and has significant hypoglycemic effect in STZ-induced diabetic mice.It is a potential hypoglycemic agent of treatment diabetes and its complication." @default.
- W2371489664 created "2016-06-24" @default.
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- W2371489664 date "2009-01-01" @default.
- W2371489664 modified "2023-09-23" @default.
- W2371489664 title "Effects of Alcoholic Extracts of Averrhoa carambola L. Root on Blood Glucose Level and Lipid Peroxidation in Diabetic Mice" @default.
- W2371489664 hasPublicationYear "2009" @default.
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