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- W2371545614 abstract "Objective To observe the effects of intrathecal injection of anti-somatostatin serum(ASSS) on electric acupuncture(EA) analgesia and β-EP in rats with adjuvant-induced arthritis(AA),and explore potential mechanism of analgesia.Methods AA rats were taken as a model of pain caused by inflammation,and pain threshold as the index,the effect of intrathecal injection of ASSS on pain threshold and EA was observed;the levels of β-EP in spinal cord and hypothalamus were detected byusing radioimmunoassay. Results Intrathecal ASSS remarkably reduced the threshold of pain,lower the analgesic effects of EA.EA increased the β-EP level in spinal cord and hypothalamus,which further raised the levels of β-EP in central nervous system.Conclusion Endogenous somatostatin plays an important role in analgesic modulation with notable effect of pain relief and closely associated with enhancement of EA,the mechanism of analgesia might be related to β-EP level of central nervous system." @default.
- W2371545614 created "2016-06-24" @default.
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- W2371545614 date "2010-01-01" @default.
- W2371545614 modified "2023-09-25" @default.
- W2371545614 title "EFFECTS OF INTRATHECAL INJECTION OF ANTI-SOMATOSTATIN SERUM ON ELECTRIC ACUPUNCTURE ANALGESIA AND β-ENDORPHINS IN RATS WITH ADJUVANT-INDUCED ARTHRITIS" @default.
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