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- W2371566138 abstract "Objective To study the hypnotic and immunoregulation effects of different active ingredients of Eucommia ulmoides Oliv. bark on mice,and to investigate the interaction. Methods After taking triazolam and distilled water respectively,the mice sleeping-behavior state was observed and recorded;the ratio of sleeping mice was recorded after taking different of ingredients Eucommia ulmoides Oliv. combining with pentobarbital sodium at subliminal dose,and mice latent period and sleeping time at supraliminal dose. Measure the content of interleukin-1β(IL-1β) in mice brain with enzyme-linked immunosorbent assay (ELISA),weigh spleen and thymus of mice. Results The effects of different of ingredients Eucommia ulmoides Oliv. on mice sleeping-behavior state varied at the position of hypnotic active time, comparing with positive control.The ratio of sleeping mice was improved and the latent period shortened and the sleeping time prolonged;the levels of IL-1β in mice brain were decreased at different degrees. Conclusion The three kinds of active ingredients had effects on mice falling to sleep and adjusting immunity.Ethyl Acetat (EtOAc) ingredients showed the best effects." @default.
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- W2371566138 date "2006-01-01" @default.
- W2371566138 modified "2023-09-26" @default.
- W2371566138 title "Study on Hypnotic and Immunoregulation Effects of Different Active Ingredients of Eucommia ulmoides Oliv. Bark on Mice" @default.
- W2371566138 hasPublicationYear "2006" @default.
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