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- W2371569277 abstract "Objective: To observe the effects of zinc on the activity of serum myocardial enzymes during myocardial ischemia -reperfusion (MIR) injury in rabbits.Methods: The model of MIR was made by ligating the left anterior descending coronary artery for 40 minutes and then reperfusing it for 3 hours .The activity of serum LDH and CK in different time points were observed . The rabbits were killed after being reperfused for 3 hours .Their hearts were excised and were made pathological examination.The sham-operated control and zinc administration group were designed.Results:The result shows that the activity of serum LDH and CK in the MIR group increased significantly in the time when ischemia had lasted for 40 minutes or reperfusion had lasted for 1 hours ,2 hours and 3 hours .The structure of myocardium was destructed severely in the MIR group. The activity of serum LDH and CK in the zinc administration group was lower than that of the MIR group but was higher than the sham-operated control. The destruction of the myocardial structure in the zinc administration group was slighter than the MIR group.Conclusion: Appropriate zinc administration has some protective effects in the myocardium ischemia-reperfusion injury in rabbits." @default.
- W2371569277 created "2016-06-24" @default.
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- W2371569277 date "2004-01-01" @default.
- W2371569277 modified "2023-09-23" @default.
- W2371569277 title "Effect of zinc on serum myocardial enzymes during myocardium ischemia reperfusion in rabbits" @default.
- W2371569277 hasPublicationYear "2004" @default.
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