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- W2371569369 abstract "Aim To evaluate the relationship between genetic polymorphisms of HLA-DQ and systemic lupus erythematosus in Chinese population.Methods Odds ratios(OR) of HLA-DQ allele distributions in patients with SLE against healthy controls were analysed.All the relevant studies were identified,poor qualified studies excluded and the publication bias was evaluated.The Meta-analysis software,Revman 4.2,was applied for investigating heterogeneity among individual studies and for summarizing all the studies.Results DQA1*0102 and DQB1*0601 were the risky alleles(all P0.05) in Chinese population,whose pooled OR values were 1.82,1.95.DQA1*0301,DQA1*0302,DQA1*0601,DQB1*0301,DQB1*0302,DQB1*0401 and DQB1*0503 were the protective alleles(all P0.05),whose pooled OR values were 0.72,0.43,0.36,0.40,0.39,0.24,0.41 respectively.Conclusions In Chinese population,some HLA-DQ alleles are associated with the SLE,and these associations are different from those in other populations." @default.
- W2371569369 created "2016-06-24" @default.
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- W2371569369 date "2006-01-01" @default.
- W2371569369 modified "2023-09-25" @default.
- W2371569369 title "A meta-analysis of the association of HLA-DQ polymorphism and systemic lupus erythematosus in Chinese population" @default.
- W2371569369 hasPublicationYear "2006" @default.
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