Matches in SemOpenAlex for { <https://semopenalex.org/work/W2371574941> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2371574941 abstract "Objective: The previous research indicated that HWAP I has analgesic effect in rat on physiological pain, acute and subacute pain. The present study was undertaken to compare antinociceptive properties of HWAP I and morphine in rats with chronic neuropathic pain. Methods: Chronic neuropathic pain was produced by placing a single polyethylene tube of varied ID around the rat's sciatic nerve, and the model is very similar to the CCI model. Five days after the surgery, different doses of HWAP I and morphine were administered epidurally respectively. Radiant heat method and tactile mechanical stimulating method were used to acesses the analgesic effects 30, 60, 120 minutes after the administration. Results: 20 μg/kg and 40 μg/kg HWAP I blocked the established heat hyperalgesia and mechanical allodynia in the injured hindpaw. Injection of 40 μg/kg morphine produced immediate and short lasting blockade effect on heat hyperalgesia bilaterally but not the allodynia. Conclusion: Epdurally administered HWAP I could allay the rat's sciatic nerve cuff induced neuropathic pain." @default.
- W2371574941 created "2016-06-24" @default.
- W2371574941 creator A5010091133 @default.
- W2371574941 date "2002-01-01" @default.
- W2371574941 modified "2023-09-25" @default.
- W2371574941 title "EFFECTS OF EPIDURAL ADMINISTRATION OF HUWENA ANALGESIC PEPTIDE-I (HWAP-I) IN RATS WITH CHRONIC NEUROPATHIC PAIN" @default.
- W2371574941 hasPublicationYear "2002" @default.
- W2371574941 type Work @default.
- W2371574941 sameAs 2371574941 @default.
- W2371574941 citedByCount "0" @default.
- W2371574941 crossrefType "journal-article" @default.
- W2371574941 hasAuthorship W2371574941A5010091133 @default.
- W2371574941 hasConcept C126322002 @default.
- W2371574941 hasConcept C15490471 @default.
- W2371574941 hasConcept C170493617 @default.
- W2371574941 hasConcept C2777107010 @default.
- W2371574941 hasConcept C2777389121 @default.
- W2371574941 hasConcept C2777610700 @default.
- W2371574941 hasConcept C2777883359 @default.
- W2371574941 hasConcept C2779245659 @default.
- W2371574941 hasConcept C2780820201 @default.
- W2371574941 hasConcept C2781149210 @default.
- W2371574941 hasConcept C42219234 @default.
- W2371574941 hasConcept C71924100 @default.
- W2371574941 hasConceptScore W2371574941C126322002 @default.
- W2371574941 hasConceptScore W2371574941C15490471 @default.
- W2371574941 hasConceptScore W2371574941C170493617 @default.
- W2371574941 hasConceptScore W2371574941C2777107010 @default.
- W2371574941 hasConceptScore W2371574941C2777389121 @default.
- W2371574941 hasConceptScore W2371574941C2777610700 @default.
- W2371574941 hasConceptScore W2371574941C2777883359 @default.
- W2371574941 hasConceptScore W2371574941C2779245659 @default.
- W2371574941 hasConceptScore W2371574941C2780820201 @default.
- W2371574941 hasConceptScore W2371574941C2781149210 @default.
- W2371574941 hasConceptScore W2371574941C42219234 @default.
- W2371574941 hasConceptScore W2371574941C71924100 @default.
- W2371574941 hasLocation W23715749411 @default.
- W2371574941 hasOpenAccess W2371574941 @default.
- W2371574941 hasPrimaryLocation W23715749411 @default.
- W2371574941 hasRelatedWork W1918764080 @default.
- W2371574941 hasRelatedWork W1972363175 @default.
- W2371574941 hasRelatedWork W1975195985 @default.
- W2371574941 hasRelatedWork W2037284859 @default.
- W2371574941 hasRelatedWork W2052319364 @default.
- W2371574941 hasRelatedWork W2060581087 @default.
- W2371574941 hasRelatedWork W2067763109 @default.
- W2371574941 hasRelatedWork W2094749427 @default.
- W2371574941 hasRelatedWork W2105016973 @default.
- W2371574941 hasRelatedWork W2148516534 @default.
- W2371574941 hasRelatedWork W2258450307 @default.
- W2371574941 hasRelatedWork W2280956917 @default.
- W2371574941 hasRelatedWork W2322119896 @default.
- W2371574941 hasRelatedWork W2359029714 @default.
- W2371574941 hasRelatedWork W2360209517 @default.
- W2371574941 hasRelatedWork W2364331501 @default.
- W2371574941 hasRelatedWork W2374150157 @default.
- W2371574941 hasRelatedWork W2375395102 @default.
- W2371574941 hasRelatedWork W2389977428 @default.
- W2371574941 hasRelatedWork W3159446183 @default.
- W2371574941 isParatext "false" @default.
- W2371574941 isRetracted "false" @default.
- W2371574941 magId "2371574941" @default.
- W2371574941 workType "article" @default.