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- W2371596985 abstract "Objective To explore the dynamic changes of platelet count in patients after cardiovascular operation,the risk factors inducing plate-reduction,and prognostic value of thrombocytopenia.Methods Ninety-nine patients,consisted of 61males and 38females with average age of 56.6±12.1(19―85)yrs,received cardiovascular operation from Nov.2008to Sep.2009.The age,gender,operation type,cross clamping time,bypass time,correlative outcomes and platelet counts at 1,2,3,5,7and 9days after cardiovascular operation were recorded.The patients were divided into normal group(n=66),infection group(n=23)and death group(n=10) according to the therapeutic results,the changes and variations of platelet counts in the three groups were analyzed.Meanwhile,the patients were divided into thrombocytopenia group(n=51)and non-thrombocytopenia group(n=48)according to the postoperative platelet count,and the infection rate and mortality were analyzed.The risk factors of postoperative thrombocytopenia and correlation between thrombocytopenia and mortality were analyzed by logistic regression analysis.Results After cardiovascular operation,the platelet count decreased significantly on the 3rd day in all patients and then raised gradually,and the damping was larger in infection group and death group than in normal group(P0.01).The infection rate and mortality were significantly higher in thrombocytopenia group than in non-thrombocytopenia group(54.9%vs 6.3%,χ2=27.213,P=0.000;19.6%vs 4.2%,χ2=5.535,P=0.019).The postoperative thrombocytopenia was closely associated with patients'age and bypass time(age:χ2=7.337,P=0.007,OR=0.943;bypass time:χ2= 14.666,P=0.000,OR=0.977).There was a significantly association between postoperative thrombocytopenia and mortality(χ2= 4.603,P=0.032,OR=0.178).Conclusions Infection rate and mortality may increase in patients with postoperative thrombocytopenia. Age and bypass time are the risk factors of postoperative thrombocytopenia,and postoperative thrombocytopenia is the risk factor of death." @default.
- W2371596985 created "2016-06-24" @default.
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- W2371596985 date "2010-01-01" @default.
- W2371596985 modified "2023-10-12" @default.
- W2371596985 title "Changes and prognostic value of platelet count in patients after cardiovascular operation" @default.
- W2371596985 hasPublicationYear "2010" @default.
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