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- W2371602273 abstract "OBJECTIVE:To screen the optimum formulation of bergenin tablet and to establish an analysis method for measuring the content of bergenin in the tablets METHODS:The L3(34) orthogonal table and the parameter of in vitro dissolubility(Td) was employed to select the optimum formulation by taking LS-HPC,tween-80-starch,and starch as the three main factors,and three levels were adopted for each-factor The dual-wavelength spectrophotography was employed to determine the content of bergenin in the tablets RESULTS:The experimental results indicated that LS-HPC and tween-80-starch were the chief factors of influencing dissolution of tablet(P0 01),and starch had no statistic significance(P0 05) The optimum formulation was composed of bergenin:0 125g,Ls-HPC:0 0 186g,tween 80-starch:0 0 248g,starch:0 1 354g,magnesium stearate:0 0 032g The dual-wavelength spectrophotography was convenient and accurate The average recovery rate of bergenin was (100 92±0 87)%(n=8) CONCLUSION:The formulation has merits of low price of supplementary materials,rapid release of effective component,simple manufacture technique,and stability in quality" @default.
- W2371602273 created "2016-06-24" @default.
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- W2371602273 date "2002-01-01" @default.
- W2371602273 modified "2023-09-23" @default.
- W2371602273 title "Experiment Study on the Quality Standard and Formulation Screening of Bergenin Tablets" @default.
- W2371602273 hasPublicationYear "2002" @default.
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