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- W2371621346 abstract "Chitosan/hydroxyapatite(CS/HA) composite with excellent mechanical properties was prepared via in situ precipitation.In this method,the calcium and phosphorus precursors were firstly added into the chitosan solution,dispersed homogeneously.Then the solution was precipitated in 6%(by mass) NaOH solution.The precipitated hydrogel rods were then cross-linked in sodium tripolyphosphate-trisodium phosphate(TPP-TSP) solution.The properties of the composites were characterized by means of TEM,FTIR,XRD and the three point bending test.Additionally,burn-out tests were also carried out to determine the dispersive uniformity of the two phases.The results showed that the synthesized HA was nanometer crystals and dispersed uniformly in chitosan matrix.The bending strength and modulus of CS/HA were 133 MPa and 6.8 GPa,respectively.Cell compatibility was studied by culturing pre-osteoblasts(MC3T3-E1) in extraction of the material,through MTT assay.Results of MTT assay indicated that the CS/HA material was good in biocompatibility with pre-osteoblasts.All of the results indicated that the CS/HA composite is a potential material as internal fixation of bone fracture." @default.
- W2371621346 created "2016-06-24" @default.
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- W2371621346 date "2010-01-01" @default.
- W2371621346 modified "2023-09-23" @default.
- W2371621346 title "Preparation and Cell Compatibility of Chitosan-hydroxyapatite Composite for Bone Repair" @default.
- W2371621346 hasPublicationYear "2010" @default.
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