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- W2371647553 abstract "AIM:To explore the effect of enriched environment on emotional behaviour in senescence accelerated-prone mice 8(SAMP8).METHODS:Three-month female SAMP8 and 3-month female senescence accelerated-resistant mice1(SAMR1)were divided into Enriched Environment(EE)group(n=16)and Standard Environment(SE)group(n=10)by random.After 3 months,the emotional behaviour was tested by Elevated Plus-Maze(EPM)and brain derived neurotrophic factor(BDNF)mRNA expression in hippocampus was tested by RT-PCR.RESULTS:EE mice had higher open arm entry percentage(OE%)and open arm time percentage(OT%)compared with SE mice(P0.01).EE mice had higher BDNF mRNA expression in hippocampus compared with SE mice(P0.01).CONCLUSION:EE could improve BDNF mRNA expression in hippocampus of SAMP8.EE also could change the emotional behaviour,which showed that EE could reduce the anxiety behaviour of SAMP8." @default.
- W2371647553 created "2016-06-24" @default.
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- W2371647553 date "2009-01-01" @default.
- W2371647553 modified "2023-09-26" @default.
- W2371647553 title "Effect of enriched environment on emotional behaviour in senescence accelerated-prone mice 8" @default.
- W2371647553 hasPublicationYear "2009" @default.
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