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- W2371670820 abstract "OBJECTIVE To establish a method for the determination of mildronate and related substances. METHODS Using HPLC-ELSD method, the related substances were separated on a CN - 3 column(4.6 mm × 250 mm,5 μm,Inertsil), and the mobile phase consisted of water and acetonitrile(80:20) .The ELSD detection temperature was 90 ℃ , and the gas rate was 2.5 mL·min-1 .RESULTS The liner range was 10.3 - 814.4 μg · mL-1 .The RSD of precision was 0.41% for intra-run validation and 1.63% for inter-run validation. CONCLUSION This method was simple and accurate to determine mildronate and the related substance." @default.
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- W2371670820 date "2005-01-01" @default.
- W2371670820 modified "2023-09-25" @default.
- W2371670820 title "Determination of mildronate and related substances by HPLC-ELSD" @default.
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