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- W2371679041 abstract "Objective:To investigate the hypoglycemic effect and mechanism of Gynura Medica extraction on T2DM rats.Methods:Male Sprague Dawley(SD) rats were fed with high fatty and high sugar diet for 4 weeks,then Streptozotocin(STZ) was injected intraperitioneally to make rat model of T2DM.The diabetic rats were randomly divided into six groups:normal control group,diabetic model group,Metformin group,high dose of Gynura Medica extraction,middle dose of Gynura Medica extraction and low dose of Gynura Medica extraction.Blood glucose,TC,TG,blood serum insulin,oral glucose tolerance test(OGTT) were detected after the rats given drugs for 21 days.Results:Gynura Medica extraction has obvious glucose-lowering effect on T2DM rats.It can improve T2DM rats lipid peroxidation and hyperinsulinism.Conclusion:Gynura Medica extraction has good effect for prevention and curing of T2DM rats.The mechnism of hypoglycemic effect may relate to lipid peroxidation and hyperinsulinism." @default.
- W2371679041 created "2016-06-24" @default.
- W2371679041 creator A5006120606 @default.
- W2371679041 date "2011-01-01" @default.
- W2371679041 modified "2023-09-23" @default.
- W2371679041 title "Study on The Hypoglycemic Effects and Mechanism of Gynura Medica Extraction In T2DM Rats" @default.
- W2371679041 hasPublicationYear "2011" @default.
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