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- W2371680903 abstract "Objective To investigate the lung function and airway responsiveness (AHR) of the adult with asthma during their clinical remission period.Methods Thirty-four asthmatic patients in clinical remission period underwent lung function and bronchial provocation test.FEV 1/FVC≥70% was regared as normal or near normal and V 50 or V 25≤70% prediction as abnormal function of small airway.Bronchial provocation test with methacholine were applied to assese the airway reactivity and a concentration of methacholine less than 12.8 μmol inducing a drop of 20% in the FEV 1 (PC20-FEV 1) was regarded as AHR.Positive rates of airway provocation test were compared in those with normal and abnormal lung function.Results In 34 asthmatic patients,26 (76.5%) had abnormal function of small airways and 23 (67.7%) had AHR.There was significant difference in AHR between the patient with normal and abnormalung lung function (P0.01).Conclusions The asthmatic patients during clinical remission period still exhibit abnormal small airway function and AHR indicating persistent airway inflammation.Anti-inlammatory therapy is still necessary during the remission period and the follow-up of lung function is valuble to guild stepwise therapy." @default.
- W2371680903 created "2016-06-24" @default.
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- W2371680903 date "2005-01-01" @default.
- W2371680903 modified "2023-09-23" @default.
- W2371680903 title "The lung function and bronchial hyperresponsiveness of the asthmatic patients during their remission period" @default.
- W2371680903 hasPublicationYear "2005" @default.
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