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- W2371704570 abstract "Objective To investigate the efficacy and safety of a new cryoablation catheter on the atrioventricular node. The histology and ultrastructure of the lesions produced by hypothemal energy in the myocardium were also examinated. Methods Electrophysiological studies with recordings of point of Wenckebach block,2:1 point,AH interval,HV interval were performed on 10 mongrel dogs with different temperature( -25℃ and -40℃). Then cyroablation with the lowest temperature of -75℃ was taken for 2 min or 4 min. Results Transient AV conduction block was successfully induced with mild hypothermal cryoablation (-40℃)in 60 s, and disappeared in 60 s after cryoablation. Complete atrioventriular conduction block was achieved in 3 of 5 dogs (60% ) with -75℃ for 2 minutes,in all the five dogs (100% ) with -75℃ for 4 minutes cryoablation. Histological modifications of myocardium induced by cryoablation showed heterogeneous necrosis and swelling of the myocardium. Conclusions One distinct feature that characterizes the positive site of cryoenergy is ice mapping and reversibility. It allows for prediction of success prior to full delivery of the energy and reduces the lesion of normal AV conduction. The lowest temperature of -75℃ may block local conduction of atrioventricular node permanently." @default.
- W2371704570 created "2016-06-24" @default.
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- W2371704570 date "2005-01-01" @default.
- W2371704570 modified "2023-09-28" @default.
- W2371704570 title "Effect of cryoablation on the atrio-ventricular conduction of canine' s heart" @default.
- W2371704570 hasPublicationYear "2005" @default.
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