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- W2371736006 abstract "Objective To investigate whether there are statistical differences of fractional anisotropy between multiple sclerosis (MS) patients and normal volunteers and whether this index correlated with expanded disability status score (EDSS) in MS patients by using diffusion tensor tractography (DTT), and to determine the role of this index in the study of MS. Methods Thirty-six volunteers and 64 patients with remitting-relapsing multiple sclerosis underwent diffusion tensor imaging. Then corpus callosum was reconstructed, and FA values of them were computed. Differences of FA values of corpus callosum between MS patients and normal volunteers were investigated, and correlation of this index with EDSS was also determined. Results There was no sex difference of the mean FA value of corpus callosum (P0.05), its mean FA value was 0.506 ±0.020. the mean FA value of corpus callosum (0.465±0.033) of MS group was significantly lower than that of normal contrast group. The mean FA value of corpus callosum of cerebral type of MS (0.456±0.036) was significantly lower than that of spinal type (0.475±0.025)(P0.05). In MS patients, there wasn't correlation of FA of corpus callosum with EDSS (r=-0.104,P0.05). Conclusion The mean FA value of corpus callosum of MS group was significantly abnormal, but it can not reflect the status of disability in MS patients." @default.
- W2371736006 created "2016-06-24" @default.
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- W2371736006 date "2005-01-01" @default.
- W2371736006 modified "2023-09-25" @default.
- W2371736006 title "Quantitative study of corpus callosum in patients with multiple sclerosis using diffusion tensor tractography" @default.
- W2371736006 hasPublicationYear "2005" @default.
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