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- W2371736139 abstract "Objective:To analyze diagnostic value of anti-mutated citrullinated vimentin (anti-MCV) antibody for rheumatoid arthritis (RA).Methods:The anti-MCV antibodies were determined in 225 patients with RA,77 non-RA patients and 80 normal volunteers. The diagnostic value of anti-MCV and antibody combination of anti-MCV with anti-cyclic citrullinated peptide antibodies (anti-CCP) were assessed and compared with that of anti-CCP and Rheumatoid factors (RF).Results:The sensitivities of anti-MCV,RF-IgM and anti-CCP in the 225 patients were of 74.67%,91.71% and 77.78%;With specifities of 91.71%,65.33% and 94.27%.The sensitivity and specificity of the combination of anti-MCV with anti-CCP was 60.89% and 99.36%.Anti-MCV and anti-CCP were valuable criteria for diagnosis of RA where RF was negative (30% and 26% respectively).Anti-MCV presented a significantly positive correlation with anti-CCP and RF(P0.01).Anti-MCV presented positive correlation with ages,course,ranks of joint function,number of tender joints,ESR,CRP,stages of radiology and duration of morning stiffness(P0.01 or P0.05).Anti-MCV presented no correlation with sex,gripping power and number of swollen joints(P0.05).Conclusion:Anti-MCV is a valuable index for the diagnosis of RA." @default.
- W2371736139 created "2016-06-24" @default.
- W2371736139 creator A5052248008 @default.
- W2371736139 date "2008-01-01" @default.
- W2371736139 modified "2023-09-23" @default.
- W2371736139 title "Detection of the antibodies of anti-mutated citrullinated vimentin in diagnosis of rheumatoid arthritis" @default.
- W2371736139 hasPublicationYear "2008" @default.
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