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- W2371736798 abstract "Objective To explore the practicability of establishing lung cancer model through the plant with rabbit VX2 puncture, and compare it with another two models respectively injected through trachea and chest with cell suspension. Methods 18 big white rabbits of Newzealand were divided into 3 groups randomly and averagely. Rabbits in group A received percutaneous puncture through chest and injected with VX2 tumor tissue mass under the guide of CT; rabbits in group B accepted the same puncture and were injected with cell suspension; in addition, rabbits in group C were planted through the trachea with the lead of DSA. The diameter and the CT value of the tumor were measured 14, 21 and 28 days after the planted operation. Results the successful rates in group A and B were 100%, while no tumor were detected in group C, and the tumor can be identified during 14~21 days. The diameter was (1.5±0.5) cm in group A, and (1.0±0.5) cm in group B. At the same time the CT value was about (30±14) Hu in group A, and (29±16) Hu in group B. The rate of tumor metastasis in group A was 1/6, and the survival time was (28±6) d; Meanwhile, the rate in group B was 4/6, and the survival the time was (16±5) d. There was statistically significant in survival time and the rate of tumor metastasis between group A and B. Conclusion It is a convenient and effective way to establish the rabbit VX2 lung cancer by the tissue mass injection through chest with CT guidance." @default.
- W2371736798 created "2016-06-24" @default.
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- W2371736798 date "2009-01-01" @default.
- W2371736798 modified "2023-09-23" @default.
- W2371736798 title "Reproduction and evaluation of VX2 lung cancer model in rabbits" @default.
- W2371736798 hasPublicationYear "2009" @default.
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