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- W2371785909 abstract "Objective:To determine the optimal strategy for the use of glycoprotein Ⅱb / Ⅲa (Gp Ⅱb / Ⅲa) inhibitors in patients with high-risk acute coronary syndromes (ACS) receiving an early invasive treatment. Methods:One hundred and sixty-two patients with high-risk ACS undergoing early percutaneous coronary syndromes were assigned to receive either routine upstream(n = 82) or deferred selective (n =80) Gp Ⅱb/Ⅲa inhibitor treatment. The authors evaluated the effects of two strategies on tissue-level perfusion using the TIMI myocardial perfusion grade (TMPG) before and immediately after PCI. Blooding complications and the 30 day composite end point events were also evaluated. Results:Among all the total 162 patients, the TMPG 0-1 perfusion were observed in 65 patients (40.1%). The TMPG 0-1 perfusion was significantly less frequent in routine upstream treatment (n = 27) than in deferred selective group(n = 38) before PCI(32.9% vs 47.5%, respectively; P 0.05). No differences were seen both in 30 day composite end point events and bleeding complications. Conclusion:Among high-risk ACS patients treated with an early invasive strategy, routine upstream use of Gp Ⅱb/Ⅲa inhibitors is associated with tissue-level perfusion improved and without bleeding complications increased." @default.
- W2371785909 created "2016-06-24" @default.
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- W2371785909 date "2009-01-01" @default.
- W2371785909 modified "2023-09-26" @default.
- W2371785909 title "R outin upstream initiation vs deferred selective use of glycoprotein IIb/IIIa inhibitors in high-risk acute coronary syndromes" @default.
- W2371785909 hasPublicationYear "2009" @default.
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