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- W2371793911 abstract "Aim:To investigate the expression of hMSH2 mRNA in various differentiated grades of gastric cancer and normal gastric mucosa.Methods:A total of 27 cases of gastric cancer tissues (well, moderately and poorly differentiated cancers were 5, 9 and 13 cases ,respectively) and 19 cases of normal gastric mucosa were examined by using in situ hybridization for the expression of hMSH2 mRNA.Results:In comparison with the normal mucosa, the number of hMSH2 mRNA signal positive cells in the gastric cancer reduced sighificantly( P 0.05).The mumber of positive signal cells in poorly differentiated cancers was significantly less than those in well and moderately differentiated cancers ( P 0.01).Conclusion: There is a positive relationship between the expression of hMSH2 mRNA and the grade of gastric cancer differentiation.hMSH2 may induce the cell differentiation and regulate the gastric cancer cells in transcriptive level." @default.
- W2371793911 created "2016-06-24" @default.
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- W2371793911 date "2001-01-01" @default.
- W2371793911 modified "2023-09-22" @default.
- W2371793911 title "Expression of hMSH2 mRNA in various differentiated grades of gastric cancer tissues" @default.
- W2371793911 hasPublicationYear "2001" @default.
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