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- W2371812817 abstract "Significant advances have been made in nucleoside( nucleotide) analogues( NAs) therapy to treat chronic hepatitis B,and this therapy reduces the risk of hepatitis B virus( HBV)-related hepatocellular carcinoma( HCC) in some patients,therefore some researchers reason NAs may also benefit HBV-related HCC patients after radical hepatectomy. From 2004,there are more and more studies which investigated outcomes of antiviral therapy with NAs for HBV-related HCC. Now a systematical review has been made for these studies by bubble plots and the results show that postoperative NAs therapy not only increases recurrence-free survival rates,but also enhances overall survival rates. Patients with HCC should take NAs if they have positive HBV-DNA. For patients with no NA treatment history,the potent and high-resistance-barrier drugs should be the best choice,and close monitoring of HBV resistance at the same time is indispensable;moreover,for lamivudine-resistant patients,adefovirdipivoxil plus lamivudine or entecavir should be used for long term treatment." @default.
- W2371812817 created "2016-06-24" @default.
- W2371812817 creator A5091617684 @default.
- W2371812817 date "2015-01-01" @default.
- W2371812817 modified "2023-09-24" @default.
- W2371812817 title "Nucleoside / Nucleotide Analogues for Hepatitis B Virus-Related Hepatocellular Carcinoma after Radical Hepatectomy" @default.
- W2371812817 hasPublicationYear "2015" @default.
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