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- W2371840670 abstract "Objective: To explore the relationship between a polymorphism in the glucocorticoid recepter(GR) gene and plasm glucose, insulin, lipids in abdominal obesity. Methods: The genotypes of GR gene were detected by allele-specific PCR method, and plasm lipids, fasting and 120 min glucose, insulin loading oral glucose(75 g) were measured. Results: TT genotype compared with CC genotype in the male obese, plasma fasting glucose was significantly increased(P 0.05); but both of fasting and 120 min insulin after loading oral glucose decreased(P 0.05, P 0.01). TT genotype compared with CC genotype in the female obese, plasma TG was increased(P 0.05). Conclusion: This result indicated that the TT genotypes of codon 678 in exon 8 of glucocorticoid recepter gene have some effect on plasma lipids, glucose and insulin secretion with sex difference." @default.
- W2371840670 created "2016-06-24" @default.
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- W2371840670 date "2004-01-01" @default.
- W2371840670 modified "2023-09-23" @default.
- W2371840670 title "Association of Polymorphism in the Glucocorticoid Recepter Gene and Plasm Glucose,Insulin, Lipids in Abdominal Obesity" @default.
- W2371840670 hasPublicationYear "2004" @default.
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