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- W2371844883 abstract "Objective To study the hypoglycemic mechanism of tea polysaccharide.Methods The inhibitory activities of tea polysaccharide against alpha-glucosidase(EC 3.2.1.20)and alpha-amylase(EC 3.2.1.1)were tested by colorimetric method,glucose uptake into brush border membrane vehicles were determined by rapid filtration method.Results In alpha-glucosidase inhibitory assay,tea polysaccharide showed potent inhibitory activity with IC50value of 3.2g/L;while inhibitory effect of tea polysaccharide on alpha-amylase was low,the inhibitory activity were about 10% at the concentration of 1 g/L.Tea polysaccharide also significantly decreased glucose transport potency of brush border membrane vehicle of rabbit small intestine with IC50 value of 15g/L.Conclusion Tea polysaccharide can inhibit alpha-glucosidase and alpha-amylase activities and glucose uptake into brush border membrane vehicles,therefore can delay carbohydrate digestion and absorption." @default.
- W2371844883 created "2016-06-24" @default.
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- W2371844883 date "2007-01-01" @default.
- W2371844883 modified "2023-09-27" @default.
- W2371844883 title "Study on hypoglycemic mechanism of tea polysaccharide" @default.
- W2371844883 hasPublicationYear "2007" @default.
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