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- W2371862889 abstract "Objective:To investigate the influence of freeze-dried cancellous bone (FDB) on mesenchymal stem cells’(MSCs’) osteogenic potential.Method:MSCs from adult human bone marrow were isolated and cultured,then were seeded onto FDB.The adhension of MSCs on FDB was investigated by scanning electron microscopy.The composite of FDB with MSCs having been incubated for different length of time(2 hours,1 day,10 days) in vitro were implanted into athymic mice.The implants were evaluated by histology and quantitative histomorphometry at 2,4 and 8 weeks respectively.Result:MSCs grew in both the surface pores and the inner pores of FDB.All the implants showed the good osteogenic abaility.There was no significant relationship between the bone amount of implants and the length of incubating time within 10 days in vitro.Conclusion:There is good biocompatibility between MSCs and FDB.Length of incubating time( within 10 days) on FDB has no effect on the cells’ osteogenic potential." @default.
- W2371862889 created "2016-06-24" @default.
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- W2371862889 date "2005-01-01" @default.
- W2371862889 modified "2023-09-27" @default.
- W2371862889 title "The influence of freeze-dried cancellous bone on mesenchymal stem cells’ osteogenic potential" @default.
- W2371862889 hasPublicationYear "2005" @default.
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