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- W2371870144 abstract "Objective:To investigate plasma contents of endothelin (ET) in patients with type 2 diabetes mellitus (DM) and study the relationship between myocardial function and ET in these patients. Methods:83 diabetic patients and 12 healthy subjects were devided into two groups. Plasma ET was measured with immnoradiometic assay (IRMA). The parameters of the diastolic and systolic function were measured with echocardiography. Results: The plasma level of ET increased significantly according to the severity of cardiac dysfunction. The plasma ET concentration was elevated markedly in the systolic and both diastolic and systolic dysfunction group (P 0. 01) . The plasma level of ET had significant negative correlation with LVEF (r = -0. 21 ,P 0. 05). The results indicate that ET levels in serious diabetic patients are significantly higher than patients with well controlled. Conclusion: The plasma levels of ET increased significantly according to the severity of systolic and diastolic cardiac dysfunction. It might be valuable laboratory plasma marker for diagnosis of the cardiac function of diabetic patients. The controlled levels of fasting plasma glucose (FPG) markedly associated with the levels of ET in diabetic patients." @default.
- W2371870144 created "2016-06-24" @default.
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- W2371870144 date "2005-01-01" @default.
- W2371870144 modified "2023-09-23" @default.
- W2371870144 title "A clinical study of the relationship between myocardial function and plasma endothelin in the patients with type 2 diabetes mellitus" @default.
- W2371870144 hasPublicationYear "2005" @default.
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