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- W2371872820 abstract "To predict B cell epitopes of endothelial cell-specific molecule-2(ECSM2) extracellular domain.Basing on the amino acids of ECSM2 extracellular domain,the sequence specificity,secondary structure,and various parameter including polarity,hydrophilicity, flexibility and surface accessibility were analyzed with public bioinformatics tools.And then,professional tool was applied to predict potential B cell epitopes of ECSM2 extracellular domain.Finally,the data obtained from bioinformatics were comprehensively analyzed to predict the possible epitopes.The analysis showed the region encoding amino acid residues 69-93 of ECSM2 was probably the dominant epitope, because this short peptide region contains four overlapping potential epitopes.The epitopes concluded by bioinformatics provide theoretical references for isolating specific antibodies targeting vascular endothelial cell from antibody library or hybridoma cell library." @default.
- W2371872820 created "2016-06-24" @default.
- W2371872820 creator A5031166800 @default.
- W2371872820 date "2010-01-01" @default.
- W2371872820 modified "2023-09-28" @default.
- W2371872820 title "Predicting B cell epitopes of ECSM2 extracellular domain with bioinformatics" @default.
- W2371872820 hasPublicationYear "2010" @default.
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