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- W2371899571 abstract "Objective To investigate the effects of zinc deficiency on the zinc ion and zinc transporter 4 expression in hippocampal neurons.Method CD-1 mice were fed with zinc deficient diets or normal diets after weaning.The hippocampi were taken after five weeks.Autometallography,histochemistry and Western blotting were used for the detection of zinc ion content,and qualitative and quantitative detection of zinc transporter 4 expressions in the hippocampal neurons in both groups.Results The zinc ion contents were decreased in various areas of the hippocampus.And the expression of zinc transporter 4 was downregulated after zinc deficiency for 5 weeks.Conclusion The zinc deficiency might result in a decrease of zinc ion and a down-regulation expression of zinc transporter 4 in hippocampus,which may affect the homeostasis of zinc and finally affect mice's learning and memory function." @default.
- W2371899571 created "2016-06-24" @default.
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- W2371899571 date "2011-01-01" @default.
- W2371899571 modified "2023-09-27" @default.
- W2371899571 title "Effects of Zinc Deficiency on Zinc Ion and Zinc Transporter 4 Expression in Hippocampal Neurons" @default.
- W2371899571 hasPublicationYear "2011" @default.
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