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- W2371901733 abstract "Objective To investigate the clinical pathological features,immunophenotype and differential diagnosis of interdigital dentritic cell sarcoma.Methods We reported two cases of the uncommon interdigital dentritic cell sarcoma,with review of the literature.Results Two patients had painless regional lymphadenectasis as well as skin manifestations.Under microscope,the tumor boundary was unclear and appeared in nest shape,partially in fascicular or whorled growth pattern.The cells were diffusely distributed,in spindle,round and oval shapes,with rich,translucent or mild eosinophilous cytoplasm.Nucleus was round and vacuolar with obvious nucleoli.Some of them had nuclear groove.There were often more lymphocytes and plasmacytes infiltration.The immunohistochemical features(vimentin +,S-100 +,CD68 + /-,Ki-67 +,CD21-,CD35-,HMB45,MelanA,CD4-,CgA-) were supported for diagnosis.Conclusions Dendritic cell sarcoma is a rare malignant tumor,and its diagnosis depends on pathological examination and immunohistochemistry,when necessary,electron microscopy.It must be distinguished with other types of histiocytic tumors,malignant melanoma,and soft tissue tumors.Sample tumor excision may cure;but for patients with multiple or multi-organ involvement,surgery combined with radiotherapy and chemotherapy is suggested,but there is no generally accepted standard of effective programs." @default.
- W2371901733 created "2016-06-24" @default.
- W2371901733 creator A5071851360 @default.
- W2371901733 date "2010-01-01" @default.
- W2371901733 modified "2023-09-28" @default.
- W2371901733 title "Interdigital dentritic cell sarcoma:two cases report and review of literature" @default.
- W2371901733 hasPublicationYear "2010" @default.
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