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- W2371919210 abstract "Objective To study the relationship between the glutathione S transferase M1(GSTM1) gene polymorphism and genetic susceptibility in nasopharyngeal carcinoma(NPC).Methods The genetypes of GSTM1 gene in eighty patients and eighty normal controls were detected by intercontrastive polymerase chain reaction(PCR) technique.Results The frequency of GSTM1 null genetype was 60.0% in NPC,and 45.0% in normal control,the difference was significant( P 0.05,OR=1.833,95%CI:1.046～3.147);the null genetype frequency in squamous cell carcinoma(60.5%) was increased compared with adenocarcinoma(50.0%);the smokers with null genetype had a high risk of NPC(OR=2.813,95%CI:1.358～6.012, P 0.01),but the non smokers did not( P 0.05).Conclusion The polymorphism of GSTM1 gene is closely related to the susceptibility to NPC and the type of NPC." @default.
- W2371919210 created "2016-06-24" @default.
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- W2371919210 date "2002-01-01" @default.
- W2371919210 modified "2023-09-25" @default.
- W2371919210 title "Relationship Between GSTM1 Gene Polymorphism and Genetic Susceptibility in Nasopharyngeal Carcinoma" @default.
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