Matches in SemOpenAlex for { <https://semopenalex.org/work/W2371924963> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2371924963 abstract "Objective:To induce allogeneic antigen-specific CD4+CD25+ regulatory T cells in vivo and identify the function of these cells.Methods:Allogeneic antigen-specific CD4+CD25+ regulatory T cells were generated by the addition of multiple intravenous injections of ICR mice splenocytes in vivo.Spleen cells were then pooled and enriched for CD4+CD25+ T cells and CD4+CD25-T cells by negative and positive selection using MACS in vitro.Characterizations of allogeneic antigen-specific CD4+CD25+ regulatory T cells were tested by mixed lymphocyte reaction(MLR) consisting of BALB/cByJ splenocytes as responder and MMC-treated ICR splenocytes as stimulator.The abilities of these cells to respond to various stimulators and to suppress alloreactive T cells responses were tested in vitro.Results:In the MLR,allogeneic antigen-specific T cells displayed little proliferation with allogeneic-antigen existence.Furthermore,these cells inhibited the proliferative responses and IFN-γ production of naive CD4+CD25-T cells to alloantigens in vitro.Conclusion:Donor-specific splenocyte transfusion-induced CD4+CD25+ T cells were allogeneic antigen-specific.They were anergic,and retained their ability to suppress antigen-driven responses of CD4+CD25-T cells in vitro." @default.
- W2371924963 created "2016-06-24" @default.
- W2371924963 creator A5051993838 @default.
- W2371924963 date "2010-01-01" @default.
- W2371924963 modified "2023-09-23" @default.
- W2371924963 title "Induction and identification of allogeneic antigen-specific CD4~+CD25~+ regulatory T cells" @default.
- W2371924963 hasPublicationYear "2010" @default.
- W2371924963 type Work @default.
- W2371924963 sameAs 2371924963 @default.
- W2371924963 citedByCount "0" @default.
- W2371924963 crossrefType "journal-article" @default.
- W2371924963 hasAuthorship W2371924963A5051993838 @default.
- W2371924963 hasConcept C129374314 @default.
- W2371924963 hasConcept C147483822 @default.
- W2371924963 hasConcept C153911025 @default.
- W2371924963 hasConcept C154317977 @default.
- W2371924963 hasConcept C167672396 @default.
- W2371924963 hasConcept C189976730 @default.
- W2371924963 hasConcept C202751555 @default.
- W2371924963 hasConcept C203014093 @default.
- W2371924963 hasConcept C2776090121 @default.
- W2371924963 hasConcept C2780931953 @default.
- W2371924963 hasConcept C2992881475 @default.
- W2371924963 hasConcept C55493867 @default.
- W2371924963 hasConcept C67662055 @default.
- W2371924963 hasConcept C79484868 @default.
- W2371924963 hasConcept C86803240 @default.
- W2371924963 hasConcept C8891405 @default.
- W2371924963 hasConcept C95444343 @default.
- W2371924963 hasConceptScore W2371924963C129374314 @default.
- W2371924963 hasConceptScore W2371924963C147483822 @default.
- W2371924963 hasConceptScore W2371924963C153911025 @default.
- W2371924963 hasConceptScore W2371924963C154317977 @default.
- W2371924963 hasConceptScore W2371924963C167672396 @default.
- W2371924963 hasConceptScore W2371924963C189976730 @default.
- W2371924963 hasConceptScore W2371924963C202751555 @default.
- W2371924963 hasConceptScore W2371924963C203014093 @default.
- W2371924963 hasConceptScore W2371924963C2776090121 @default.
- W2371924963 hasConceptScore W2371924963C2780931953 @default.
- W2371924963 hasConceptScore W2371924963C2992881475 @default.
- W2371924963 hasConceptScore W2371924963C55493867 @default.
- W2371924963 hasConceptScore W2371924963C67662055 @default.
- W2371924963 hasConceptScore W2371924963C79484868 @default.
- W2371924963 hasConceptScore W2371924963C86803240 @default.
- W2371924963 hasConceptScore W2371924963C8891405 @default.
- W2371924963 hasConceptScore W2371924963C95444343 @default.
- W2371924963 hasLocation W23719249631 @default.
- W2371924963 hasOpenAccess W2371924963 @default.
- W2371924963 hasPrimaryLocation W23719249631 @default.
- W2371924963 hasRelatedWork W1509909867 @default.
- W2371924963 hasRelatedWork W1595092110 @default.
- W2371924963 hasRelatedWork W1961184285 @default.
- W2371924963 hasRelatedWork W1969590766 @default.
- W2371924963 hasRelatedWork W1982529683 @default.
- W2371924963 hasRelatedWork W2022221509 @default.
- W2371924963 hasRelatedWork W2040851650 @default.
- W2371924963 hasRelatedWork W2046075122 @default.
- W2371924963 hasRelatedWork W2069335042 @default.
- W2371924963 hasRelatedWork W2074220343 @default.
- W2371924963 hasRelatedWork W2079604598 @default.
- W2371924963 hasRelatedWork W2141886677 @default.
- W2371924963 hasRelatedWork W2145562912 @default.
- W2371924963 hasRelatedWork W2171966651 @default.
- W2371924963 hasRelatedWork W2527740104 @default.
- W2371924963 hasRelatedWork W2560483699 @default.
- W2371924963 hasRelatedWork W2584132785 @default.
- W2371924963 hasRelatedWork W3021575480 @default.
- W2371924963 hasRelatedWork W3028892004 @default.
- W2371924963 hasRelatedWork W4211110693 @default.
- W2371924963 isParatext "false" @default.
- W2371924963 isRetracted "false" @default.
- W2371924963 magId "2371924963" @default.
- W2371924963 workType "article" @default.