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- W2371933718 abstract "Objective: To investigate the synergistic antibacterial effect of Callicarpa nudiflora associated with Vancomycin Hydrochloride on the pneumonia model mice which were infected by methicillin-resistant staphylococcus aureus(MRSA).Methods: 96 NIH female mice were divided into 8 groups randomly,each of which was injected with 50μL bacteria(1.0×109cfu/mL) into nasal cavity to produce infected animal model and administered respectively drug by group for 10 days.Observed and noted common state,including activity,intake of water and food.After 10 days' administration of drugs,took count of leucocyte,did microbial load and pathological slice of lung.Results: Compared with model group,the absolute value of leucocyte and microbial load of each traditional Chinese drug associated with Callicarpa nudilora were reduced signiicantly(P0.05).The pathological damage alleviated signiicantly.Conclusion: Association of Callicarpa nudilora and Vancomycin Hydrochloride have synergistic antibacterial efect towards MRSA,which can improve curative efect of antibiotics and shorten the period of treatment." @default.
- W2371933718 created "2016-06-24" @default.
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- W2371933718 date "2013-01-01" @default.
- W2371933718 modified "2023-09-24" @default.
- W2371933718 title "Research on the synergistic antibacterial effect of association of Callicarpa nudiflora and Vancomycin Hydrochloride towards methicillin-resistant staphylococcus aureus" @default.
- W2371933718 hasPublicationYear "2013" @default.
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