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- W2371948557 abstract "Objective: This study was designed to find out whether urocortin was measurable in maternal plasma in an attempt to provide evidence for the hypothesis that urocortin was a regulator of utero placental vascular tone during pregnancy. Methods: We examined whether urocortin was present in maternal plasma throughout gestation using radioimmunoassay, and whether urocortin in maternal plasma was the same as synthetic urocortin using a Sephadex G 50 column. Results: Urocortin was detectable in maternal plasma from 16 weeks of gestation and the concentration remained changed as gestation progressed. Urocortin in maternal plasma eluted from a Sephadex G 50 column was at the same site as synthetic urocortin and had a calculated retention coefficient( K d) of 0.44. Conclusion: This study indicates that urocortin is measurable in maternal plasma and its concentration remains unchanged. These data provide evidence for the hypothesis that urocortin may act to regulate utero placental blood flow. [" @default.
- W2371948557 created "2016-06-24" @default.
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- W2371948557 date "2000-01-01" @default.
- W2371948557 modified "2023-09-23" @default.
- W2371948557 title "Detection of urocortin in maternal plasma" @default.
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