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- W2371963929 abstract "Objective:To study on the inhibitory effect of lentinan in combination with kappa-selenocarrageenan on leukemia and its molecular mechanism of antileukemia.Methods: The inhibitory effect of lentinan in combination with kappa-selenocarrageenan on leukemia cells was detected by MTT methods.The extent of cell apoptosis was measured by flow cytometry.The expressive levels of Fas and FasL were detected by immunochemistry assay.Results: Lentinan in combination with kappa-selenocarrageenan can inhibit the proliferation of leukemia cells.Kappa-selenocarrageenan plays tumor-suppressing roles through upregulating the expression of Fas and FasL and improving apoptosis,and lentinan by upregulating the expression of Fas but no effect on FasL.Conclusion:Lentinan and kappa-selenocarrageenan have different tumor-suppressing mechanisms.Lentinan in combination with kappa-selenocarrageenan can markedly improve the inhibiting effect on leukemia." @default.
- W2371963929 created "2016-06-24" @default.
- W2371963929 creator A5061114922 @default.
- W2371963929 date "2008-01-01" @default.
- W2371963929 modified "2023-09-23" @default.
- W2371963929 title "Experimental Study on Effect of Chinese Tradtional Medicine Polysaccharides in Combination with Selenium on P388 Leukemia Mice" @default.
- W2371963929 hasPublicationYear "2008" @default.
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