Matches in SemOpenAlex for { <https://semopenalex.org/work/W2371993886> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2371993886 endingPage "907" @default.
- W2371993886 startingPage "906" @default.
- W2371993886 abstract "OBJECTIVE: To investigate the protective and jaundice-relieving effects of gentiopicrooside (GPS) injections in mouse and rat models of chemical-induced and immune-mediated hepatic injury. METHODS: Mouse models of chemical-induced liver injury were established by CCl4 injections into the abdominal cavity, mouse models of immune-mediated liver damage by bacillus Calmette-Guerin (BCG) and lipopolysaccharide (LPS) and rat models of jaundice by oral alpha-naphthyliso-thiocyanate (ANIT). Treatment with GPS injections was administered and both of enzyme activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in the Serum were measured in the models. The serum level of total bilirubin was determined in the jaundice models. RESULTS: Compared with those of the untreated models, the enzyme activities of ALT and AST were significantly reduced in groups with a 10 day GPS treatment (P<0.001, P<0.05). Higher dosage of GPS showed more conspicuous effects in relieving the jaundice. CONCLUSION: GPS can be administered as the antagonist against CC14-induced liver injury and offers protection against immune-mediated liver damage." @default.
- W2371993886 created "2016-06-24" @default.
- W2371993886 creator A5013010662 @default.
- W2371993886 creator A5026316016 @default.
- W2371993886 creator A5056872353 @default.
- W2371993886 creator A5063912388 @default.
- W2371993886 creator A5074359387 @default.
- W2371993886 date "2001-01-01" @default.
- W2371993886 modified "2023-10-16" @default.
- W2371993886 title "Effects of gentiopicrooside injections on experimental hepatic injury." @default.
- W2371993886 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12426161" @default.
- W2371993886 hasPublicationYear "2001" @default.
- W2371993886 type Work @default.
- W2371993886 sameAs 2371993886 @default.
- W2371993886 citedByCount "0" @default.
- W2371993886 crossrefType "journal-article" @default.
- W2371993886 hasAuthorship W2371993886A5013010662 @default.
- W2371993886 hasAuthorship W2371993886A5026316016 @default.
- W2371993886 hasAuthorship W2371993886A5056872353 @default.
- W2371993886 hasAuthorship W2371993886A5063912388 @default.
- W2371993886 hasAuthorship W2371993886A5074359387 @default.
- W2371993886 hasConcept C126322002 @default.
- W2371993886 hasConcept C141071460 @default.
- W2371993886 hasConcept C185592680 @default.
- W2371993886 hasConcept C203014093 @default.
- W2371993886 hasConcept C2776294642 @default.
- W2371993886 hasConcept C2776637226 @default.
- W2371993886 hasConcept C2777513400 @default.
- W2371993886 hasConcept C2778456037 @default.
- W2371993886 hasConcept C2778754761 @default.
- W2371993886 hasConcept C2780936613 @default.
- W2371993886 hasConcept C2992872382 @default.
- W2371993886 hasConcept C55493867 @default.
- W2371993886 hasConcept C71924100 @default.
- W2371993886 hasConcept C8891405 @default.
- W2371993886 hasConcept C90924648 @default.
- W2371993886 hasConcept C98274493 @default.
- W2371993886 hasConceptScore W2371993886C126322002 @default.
- W2371993886 hasConceptScore W2371993886C141071460 @default.
- W2371993886 hasConceptScore W2371993886C185592680 @default.
- W2371993886 hasConceptScore W2371993886C203014093 @default.
- W2371993886 hasConceptScore W2371993886C2776294642 @default.
- W2371993886 hasConceptScore W2371993886C2776637226 @default.
- W2371993886 hasConceptScore W2371993886C2777513400 @default.
- W2371993886 hasConceptScore W2371993886C2778456037 @default.
- W2371993886 hasConceptScore W2371993886C2778754761 @default.
- W2371993886 hasConceptScore W2371993886C2780936613 @default.
- W2371993886 hasConceptScore W2371993886C2992872382 @default.
- W2371993886 hasConceptScore W2371993886C55493867 @default.
- W2371993886 hasConceptScore W2371993886C71924100 @default.
- W2371993886 hasConceptScore W2371993886C8891405 @default.
- W2371993886 hasConceptScore W2371993886C90924648 @default.
- W2371993886 hasConceptScore W2371993886C98274493 @default.
- W2371993886 hasIssue "12" @default.
- W2371993886 hasLocation W23719938861 @default.
- W2371993886 hasOpenAccess W2371993886 @default.
- W2371993886 hasPrimaryLocation W23719938861 @default.
- W2371993886 hasRelatedWork W2109900488 @default.
- W2371993886 hasRelatedWork W2348027891 @default.
- W2371993886 hasRelatedWork W2371993886 @default.
- W2371993886 hasRelatedWork W2378909332 @default.
- W2371993886 hasRelatedWork W2380048095 @default.
- W2371993886 hasRelatedWork W2382970129 @default.
- W2371993886 hasRelatedWork W2527702407 @default.
- W2371993886 hasRelatedWork W2950025759 @default.
- W2371993886 hasRelatedWork W3215448191 @default.
- W2371993886 hasRelatedWork W4236792208 @default.
- W2371993886 hasVolume "21" @default.
- W2371993886 isParatext "false" @default.
- W2371993886 isRetracted "false" @default.
- W2371993886 magId "2371993886" @default.
- W2371993886 workType "article" @default.