Matches in SemOpenAlex for { <https://semopenalex.org/work/W2372010533> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2372010533 abstract "Objective To explone the relationship between the mutation of the BRCA1 gene and the expression of ER,PR and CerbB-2 in sporadic Hui patients with breast cancer in Ningxia.Methods By using polymerase chain reaction(PCR) and DNA direct sequencing,paraffin imbedding and frozen tissues were obtained from 60 Hui female patients with breast caner and 15 controls with benign breast diseases.The expression of ER,PR and C-erbB-2 in breast cancer were analyzed retrospectively.Results 10 cases(16.67%) 60 cases with breast caner were found mutation on BRCA1.No mutation was identified in control group.The frequency of triple negative breast cancer(estrogen receptor,progesterone receptor and human epidermal growth factor receptor negative) in patients with BRCA1 mutation was 30%(3/10),which was higher than those with no BRCA1 mutation 4%,(χ2=4.364,P=0.037).There was negative correlation between the expression of ER and PR with lymph node status(χ2=5.735,P0.05;χ2=5.984,P0.05).Conclusion The mutation of BRCA1 gene were involved in carcinogensis of breast cancer.The expression of ER,PR,and C-erbB-2 has important clinical significance in treating and prognosis of breast cancer." @default.
- W2372010533 created "2016-06-24" @default.
- W2372010533 creator A5050013722 @default.
- W2372010533 date "2011-01-01" @default.
- W2372010533 modified "2023-09-26" @default.
- W2372010533 title "Relationship between the Mutation of BRCA1 Gene and the Expression of ER,PR and CerbB-2 in Hui Ethnic Patients with Breast Cancer in Ningxia" @default.
- W2372010533 hasPublicationYear "2011" @default.
- W2372010533 type Work @default.
- W2372010533 sameAs 2372010533 @default.
- W2372010533 citedByCount "0" @default.
- W2372010533 crossrefType "journal-article" @default.
- W2372010533 hasAuthorship W2372010533A5050013722 @default.
- W2372010533 hasConcept C104317684 @default.
- W2372010533 hasConcept C121608353 @default.
- W2372010533 hasConcept C126322002 @default.
- W2372010533 hasConcept C143998085 @default.
- W2372010533 hasConcept C49105822 @default.
- W2372010533 hasConcept C501734568 @default.
- W2372010533 hasConcept C502942594 @default.
- W2372010533 hasConcept C530470458 @default.
- W2372010533 hasConcept C54355233 @default.
- W2372010533 hasConcept C71924100 @default.
- W2372010533 hasConcept C84606932 @default.
- W2372010533 hasConcept C86803240 @default.
- W2372010533 hasConcept C98717036 @default.
- W2372010533 hasConceptScore W2372010533C104317684 @default.
- W2372010533 hasConceptScore W2372010533C121608353 @default.
- W2372010533 hasConceptScore W2372010533C126322002 @default.
- W2372010533 hasConceptScore W2372010533C143998085 @default.
- W2372010533 hasConceptScore W2372010533C49105822 @default.
- W2372010533 hasConceptScore W2372010533C501734568 @default.
- W2372010533 hasConceptScore W2372010533C502942594 @default.
- W2372010533 hasConceptScore W2372010533C530470458 @default.
- W2372010533 hasConceptScore W2372010533C54355233 @default.
- W2372010533 hasConceptScore W2372010533C71924100 @default.
- W2372010533 hasConceptScore W2372010533C84606932 @default.
- W2372010533 hasConceptScore W2372010533C86803240 @default.
- W2372010533 hasConceptScore W2372010533C98717036 @default.
- W2372010533 hasLocation W23720105331 @default.
- W2372010533 hasOpenAccess W2372010533 @default.
- W2372010533 hasPrimaryLocation W23720105331 @default.
- W2372010533 hasRelatedWork W149202455 @default.
- W2372010533 hasRelatedWork W1883413549 @default.
- W2372010533 hasRelatedWork W1927170709 @default.
- W2372010533 hasRelatedWork W2008766385 @default.
- W2372010533 hasRelatedWork W2128784131 @default.
- W2372010533 hasRelatedWork W2172892557 @default.
- W2372010533 hasRelatedWork W2187352586 @default.
- W2372010533 hasRelatedWork W2323730473 @default.
- W2372010533 hasRelatedWork W2362830376 @default.
- W2372010533 hasRelatedWork W2368719158 @default.
- W2372010533 hasRelatedWork W2378245183 @default.
- W2372010533 hasRelatedWork W2386139046 @default.
- W2372010533 hasRelatedWork W2389746945 @default.
- W2372010533 hasRelatedWork W2392403953 @default.
- W2372010533 hasRelatedWork W2399668913 @default.
- W2372010533 hasRelatedWork W2412887024 @default.
- W2372010533 hasRelatedWork W2765260918 @default.
- W2372010533 hasRelatedWork W2901229043 @default.
- W2372010533 hasRelatedWork W2936388114 @default.
- W2372010533 hasRelatedWork W3008220358 @default.
- W2372010533 isParatext "false" @default.
- W2372010533 isRetracted "false" @default.
- W2372010533 magId "2372010533" @default.
- W2372010533 workType "article" @default.