Matches in SemOpenAlex for { <https://semopenalex.org/work/W2372014186> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2372014186 abstract "Objective To investigate the effects of Xinmailong on myocardial injury in asphyxiated neonatal rats after hypoxia-ischemia and its mechanism through observing the influence of Xinmailong on the expression of NF-κB and TNF-α in myocardium.Methods A total of 96 neonatal Sprague-Dawley rats were randomly divided into three groups: control group(n=32),asphyxia group(n=32) and Xinmailong group(n=32).Rats were tested at various time points(3,6,12 and 24 hours;8 rats per time point per group).The newborn rat model of asphyxia was induced in asphyxia group and Xinmailong group.The levels of CK-MB and the pathological changes in myocardial tissue were observed.The expression of NF-κB in the myocardium was detected by immunohistochemistry and the levels of TNF-α were determined by ELISA.Results The levels of CK-MB and the expression of NF-κB and TNF-α in asphyxia group was higher than that in control group(P0.01).The highest levels were observed at 6 hours,and there was a positive correlation between NF-κB and TNF-α(r=0.979,P0.01).Compared with asphyxia group,Xinmailong significantly decreased the levels of CK-MB and the expression of NF-κB and TNF-α(P0.01).Conclusion The expression of NF-κB and TNF-α increases in myocardium of asphyxiated neonatal rats and reaches the highest levels at 6 hours.Xinmailong can protect the immature myocardium by reducing the expression of NF-κB and TNF-α in newborn rats with myocardial injury." @default.
- W2372014186 created "2016-06-24" @default.
- W2372014186 creator A5021035299 @default.
- W2372014186 date "2011-01-01" @default.
- W2372014186 modified "2023-09-24" @default.
- W2372014186 title "Effects of Xinmailong on Expression of NF-κB and TNF-α in Myocardium of Asphyxiated Neonatal Rats" @default.
- W2372014186 hasPublicationYear "2011" @default.
- W2372014186 type Work @default.
- W2372014186 sameAs 2372014186 @default.
- W2372014186 citedByCount "1" @default.
- W2372014186 countsByYear W23720141862015 @default.
- W2372014186 crossrefType "journal-article" @default.
- W2372014186 hasAuthorship W2372014186A5021035299 @default.
- W2372014186 hasConcept C126322002 @default.
- W2372014186 hasConcept C134018914 @default.
- W2372014186 hasConcept C16685009 @default.
- W2372014186 hasConcept C178790620 @default.
- W2372014186 hasConcept C17991360 @default.
- W2372014186 hasConcept C185592680 @default.
- W2372014186 hasConcept C204232928 @default.
- W2372014186 hasConcept C207886595 @default.
- W2372014186 hasConcept C2776914184 @default.
- W2372014186 hasConcept C2777730290 @default.
- W2372014186 hasConcept C2777785397 @default.
- W2372014186 hasConcept C2779914510 @default.
- W2372014186 hasConcept C2780164069 @default.
- W2372014186 hasConcept C2780678043 @default.
- W2372014186 hasConcept C42219234 @default.
- W2372014186 hasConcept C503630168 @default.
- W2372014186 hasConcept C540031477 @default.
- W2372014186 hasConcept C71924100 @default.
- W2372014186 hasConcept C7836513 @default.
- W2372014186 hasConceptScore W2372014186C126322002 @default.
- W2372014186 hasConceptScore W2372014186C134018914 @default.
- W2372014186 hasConceptScore W2372014186C16685009 @default.
- W2372014186 hasConceptScore W2372014186C178790620 @default.
- W2372014186 hasConceptScore W2372014186C17991360 @default.
- W2372014186 hasConceptScore W2372014186C185592680 @default.
- W2372014186 hasConceptScore W2372014186C204232928 @default.
- W2372014186 hasConceptScore W2372014186C207886595 @default.
- W2372014186 hasConceptScore W2372014186C2776914184 @default.
- W2372014186 hasConceptScore W2372014186C2777730290 @default.
- W2372014186 hasConceptScore W2372014186C2777785397 @default.
- W2372014186 hasConceptScore W2372014186C2779914510 @default.
- W2372014186 hasConceptScore W2372014186C2780164069 @default.
- W2372014186 hasConceptScore W2372014186C2780678043 @default.
- W2372014186 hasConceptScore W2372014186C42219234 @default.
- W2372014186 hasConceptScore W2372014186C503630168 @default.
- W2372014186 hasConceptScore W2372014186C540031477 @default.
- W2372014186 hasConceptScore W2372014186C71924100 @default.
- W2372014186 hasConceptScore W2372014186C7836513 @default.
- W2372014186 hasLocation W23720141861 @default.
- W2372014186 hasOpenAccess W2372014186 @default.
- W2372014186 hasPrimaryLocation W23720141861 @default.
- W2372014186 hasRelatedWork W2152189255 @default.
- W2372014186 hasRelatedWork W2282583684 @default.
- W2372014186 hasRelatedWork W2289365690 @default.
- W2372014186 hasRelatedWork W2356660487 @default.
- W2372014186 hasRelatedWork W2371632200 @default.
- W2372014186 hasRelatedWork W2372306576 @default.
- W2372014186 hasRelatedWork W2373823176 @default.
- W2372014186 hasRelatedWork W2434588324 @default.
- W2372014186 hasRelatedWork W2625336672 @default.
- W2372014186 hasRelatedWork W2790760102 @default.
- W2372014186 hasRelatedWork W3024692919 @default.
- W2372014186 hasRelatedWork W3026781928 @default.
- W2372014186 hasRelatedWork W3029708222 @default.
- W2372014186 hasRelatedWork W3030334925 @default.
- W2372014186 hasRelatedWork W3031969167 @default.
- W2372014186 hasRelatedWork W3149228912 @default.
- W2372014186 hasRelatedWork W3191479934 @default.
- W2372014186 hasRelatedWork W2067433916 @default.
- W2372014186 hasRelatedWork W2162112430 @default.
- W2372014186 hasRelatedWork W3142490761 @default.
- W2372014186 isParatext "false" @default.
- W2372014186 isRetracted "false" @default.
- W2372014186 magId "2372014186" @default.
- W2372014186 workType "article" @default.