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- W2372028547 abstract "Ankylosing spondylitis (AS) is an autoimmune disease which has a strong association with HLA-B27. Its pathogenesis includes the interaction between microorganism and host, the recognition of MHC class I molecule by immune cells and the imbalance of the cytokine network and so on. Unfolded protein response (UPR) participates in the development of AS. And the activation of the IL-23/IL-17 axis, which is in the downstream of UPR, may make a critical contribution to the pathogenesis. UPR and IL-23/IL-17 axis open new avenues of investigation as well as identifying new therapeutic target in this disease." @default.
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- W2372028547 date "2011-02-01" @default.
- W2372028547 modified "2023-09-24" @default.
- W2372028547 title "[Advance of research on HLA-B27 and the immunological mechanism of ankylosing spondylitis]." @default.
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