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- W2372028863 abstract "Objective To investigate the influence of thiopentone, midazolam, etomidate and propofol on the suxamethonium-induced serum potassium increase, muscle fasciculations and myalgia Methods Sixty patients, ASA class Ⅰ-Ⅱ were allocated randomly to receiving intravenous thiopentone 5mg/kg(thiopentone-group), midazolam 0.3mg/kg( midazolam-group), etomidate 0.3mg/kg(etomidate-group)or propofol 2mg/kg(propofol-group) respectively, followed by intravenous suxamethonium and tracheal intubation. Serum potassium concentration was measured before induction and intubation and after intubation. The incidences of muscle fasciculation during induction and postoperative mylgia were observed .Results As compared with that before induction ,the serum potassium levels in thiopentone- and etomidate-group increased significantly by 3.4% and 5.3% respectively after induction (P0.01), but did not significantly change in midazolam- and propofol-group(P0.05).The incidences of muscle fasciculation and postoperative myalgia inmidazolam- and propofol -group were significantly lower than in thiopentone- and etomidate -group (P0.01 or P0.05)。Conclusions Midazolam and propofol effectively reduce the suxamethonium-induced serum potassium increase, muscle fasciculations and myalgia , but thiopentone and etomidate do not." @default.
- W2372028863 created "2016-06-24" @default.
- W2372028863 creator A5074436769 @default.
- W2372028863 date "2000-01-01" @default.
- W2372028863 modified "2023-09-26" @default.
- W2372028863 title "Effect of thiopentone, midazolam, etomidate and propofol on the serum potassium increase, muscle fasciculations and myalgia following suxamethonium administration" @default.
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